SAM-e, which stands for S-adenosylmethionine, has become a popular dietary supplement used to treat osteoarthritis. SAM-e has been shown to be as effective as NSAIDs (nonsteroidal anti-inflammatory drugs) for the treatment of osteoarthritis. SAM-e can cause certain side effects, especially at higher doses.

SAM-e is a naturally occurring compound in the body. SAM-e is thought to be involved in more than 35 biochemical processes in the body. SAM-e is thought to increase chondrocytes (the cells that make up cartilage), cartilage thickness and possibly decrease chondrocyte damage.

SAM-e has been used for over 20 years in Europe to treat arthritis and depression. Since it is not marketed as a prescription medication in the United States as it is in Europe, be careful and cautious about the brand and quality of the product that you purchase. Choose a dietary supplement brand with a good reputation. Read more about side effects, dosage, and safety warnings in SAM-e: 10 Things You Should Know.

Related Resources:

• Osteoarthritis Treatment Options
• Dietary Supplements for Osteoarthritis
• 25 Effective Osteoarthritis Treatments
• What Is SAM-e? (S-adenosylmethionine)
• SAM-e as Effective as NSAIDs for Osteoarthritis?

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