In a study that compared tapentadol immediate-release tablets to oxycodone immediate-release tablets, results showed that elderly patients with moderate-to-severe low back pain or osteoarthritis pain did better with tapentadol. There were lower incidences of discontinuation due to gastrointestinal issues. Incidences of constipation and nausea were less with tapentadol also.
The results were presented at the 29th Annual Scientific Meeting of the American Pain Society. There were 158 patients given tapentadol IR compared to 45 patients who were taking oxycodone IR. All patients were 65 years or older. In this group of study participants, tolerability swung to tapentadol.
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