Deterioration of articular (joint) cartilage is the main problem associated with knee osteoarthritis. The condition can be caused by:
- previous knee injury
- repetitive strain on the knee
- fractures, ligament tear, and meniscal injury which can affect alignment and promote wear and tear
- genetics which make some people more likely to develop knee osteoarthritis
- obesity which adds stress to the weightbearing joints
- problems with subchondral bone (the bone layer underneath cartilage)
